Manchester City beat Tottenham 1-0 at Wembley on 29 October

BBC coverage

How to follow:
Listen on BBC Radio 5 live and BBC local radio; text commentary on the BBC Sport website

Tottenham boss Mauricio Pochettino says the Champions League quarter-final against Manchester City is one of his “most important matches as a coach”.

Spurs host Premier League rivals City in the first leg at the new £1bn Tottenham Hotspur Stadium.

“To play in the Champions League quarter-finals is a massive bonus for us,” said Pochettino.

“We know it’s going to be very tough. Manchester City in the last few years have been building to win everything.”

Tuesday’s game (20:00 BST kick-off) is the first of three matches with City – who are chasing an unprecedented quadruple – and Spurs this month.

‘City capable of winning quadruple’

City boss Pep Guardiola said at the weekend it would be “almost impossible” for his side to win the quadruple this season.

Having won the Carabao Cup, reached the FA Cup final and progressed to the quarter-finals of the Champions League, City are also chasing the Premier League title.

However, Pochettino believes Guardiola’s side are good enough to win all four competitions.

“If one team is capable of winning everything it is Manchester City today,” said the Argentine, who has urged his side to be “aggressive” in their second competitive game at their new home.

“I think they know and he [Guardiola] knows that we are brave playing football, going forward, being aggressive and trying to be protagonists.

“We are going to be aggressive and try to play and beat them.”

‘If you walk off they win’ – Sterling on racist abuse

‘We have to know how to handle situations’

This is City’s 52nd competitive match of the season and comes on the back of Saturday’s FA Cup semi-final win over Brighton.

“I don’t know how fresh we are in our legs and in our minds,” said Guardiola, whose side are unbeaten since 29 January.

“In the FA Cup we could have been better.”

Speaking about whether Tottenham’s new stadium could be an advantage to the hosts, Guardiola added: “The stadium is what it is, the supporters support the team more than ever in the Champions League.

“It’s up to us how we handle it. We have to know how to handle the situations, if we don’t that’s because we are not prepared to go through.”

Quadruple almost impossible, but we will try – Guardiola

City handed Aguero boost

City forward Sergio Aguero, who has missed the last two games with a muscle injury, could feature after returning to training.

Aguero has 29 goals this season, including five in the Champions League.

Full-backs Kyle Walker and Benjamin Mendy should also be available.

Tottenham will be without midfielder Eric Dier (hip), forward Erik Lamela (hamstring) and full-back Serge Aurier (hamstring).

Forward Fernando Llorente is back in the squad after he missed out against Crystal Palace last week with concussion.

‘City big favourites to beat Spurs’

Tottenham’s chance of winning the Champions League are slim, according to the Euro Club Index.